adj.不顧的；不考慮的

We will have the work done, irrespective of cost. 不管花多大代價(jià),我們也要把這項(xiàng)工作做好。

He rushed toward to help, irrespective of the consequence. 他不顧后果，沖上前去幫助。

He married her, irrespective of the will of his parents. 他違背父母的意愿與她結(jié)了婚。

irrespective常與of連用,構(gòu)成復(fù)合介詞。