
n.強啡肽
Results Three opioid peptides decreased with the course of diabetes and dynorphin A1-13was the most obvious of them. 結(jié)果3種阿片肽均隨病程的延長而下降,尤以強啡肽A1-13為明顯。
Conclusion Dynorphin A1-13 show s the most obvious decrease in relation to course and complications of diabetes. 結(jié)論糖尿病患者強啡肽A1-13下降與病程及并發(fā)癥的關(guān)系最密切。
Aim To investigate the effect of administration route on dynorphin A 1 13 (Dyn) inhibiting the withdrawal symptoms of morphine dependent rats. 目的 研究不同給藥途徑對強啡肽A1 13 (Dyn)抑制嗎啡依賴戒斷癥狀的影響。
Induction of dynorphin by CREB thereby stifles the brain's reward circuitry, inducing tolerance by making the same-old dose of drug less rewarding. 因此,CREB引發(fā)代腦啡,因而抑制了大腦的報償線路,使得同樣劑量的藥物變得比較沒有作用,而造成耐受性。
Objective:To investigate the effects of progesterone on morphine rewarding effect and levels of dynorphin A (DynA) in rat brain. 目的:觀察孕酮對于嗎啡所致獎賞效應(yīng)及相關(guān)腦區(qū)中強啡肽A水平的影響。