傷害感受器

Then the glia discharge a bevy of chemicals that prod nociceptor terminals to release neurotransmitters in the cord, thus perpetuating a pain signal. 神經(jīng)膠細(xì)胞釋出的物質(zhì)，包括生長因子和稱為細(xì)胞素的多種分子，還會讓背角神經(jīng)元變得過度活化；

There the nociceptor releases signaling molecules called neurotransmitters that activate neurons in the dorsal horn, prompting them to transmit the alarm message up to the brain. 在此，痛覺受器的神經(jīng)末梢會釋放稱為神經(jīng)傳遞物的傳訊分子，活化背角的神經(jīng)元，促使它們將警報(bào)上傳至腦部。

Alternatives to opiates are available as well.Medicines that interfere with calcium channels can prevent the release of neurotransmitters from nociceptor endings in the spinal cord. 鴉片類的替代藥物，也是有的：可干擾鈣離子通道的藥物，也就能阻斷痛覺受器的脊髓端釋放神經(jīng)傳遞物。

Keywords Nociceptor;Capsaicin;Vanilloid receptor;Dorsal root ganglion;Pain; 關(guān)鍵詞傷害性感受器;辣椒素;辣椒素受體;背根神經(jīng)節(jié);疼痛;

Keywords vesicle-associated protein;nociceptor;dorsal root ganglion;dorsal spinal cord;peripheral nerve injury;gene expression regulation;SNARE core complex; 囊泡轉(zhuǎn)運(yùn)釋放相關(guān)蛋白;背根神經(jīng)節(jié);脊髓背角;外周神經(jīng)損傷;基因表達(dá)調(diào)控;傷害性感受器;SNARE復(fù)合物;