n.葫蘆素

Objective To prepare the cucurbitacin B loaded poly(lactic-co-glycollic acid) nanospheres(CuB-PLGA-NS). 目的制備葫蘆素B聚乳酸羥基乙酸納米球。

Objective To study the distribution of cucurbitacin B loaded PLGA nanospheres in mice. 目的 研究葫蘆素B聚乳酸-羥基乙酸毫微球小鼠體內(nèi)分布。

Conclusion The results provide an important base to further study treatment of oral carcinoma using Cucurbitacin BE. 結(jié)論實驗結(jié)果為葫蘆素BE治療口腔癌的進一步研究提供了重要的依據(jù)。

Cucurbitacin B sc 0.1mg/kg or 0.2mg/kg obviously inhibited the expression of Fas and FasL, and number of apoptotic cells in dose-dependent manner. sc葫蘆素B 0 .

Results Two kinds of cancer cell lines had higher sensitivity to Cucurbitacin BE,Relative anti-tumor activitics(RAA) were 345 and 148,respectively. 結(jié)果葫蘆素BE對兩種癌細胞系均有較高的相對抗腫瘤活性（RAA值分別為345、148）。