軟骨發(fā)生, 軟骨形成

Passage of the cocultured cells didn’t influence the chondrogenesis of BMSCs . 共培養(yǎng)條件下，對(duì)細(xì)胞進(jìn)行傳代，對(duì)BMSCs繼續(xù)向軟骨細(xì)胞分化的影響不大。

Role of BMP-2 on the simvastatin-induced chondrogenesis of IVD cells was also investigated. 在辛伐他汀誘導(dǎo)大鼠椎間盤細(xì)胞的軟骨細(xì)胞生成過程中，研究BMP-2的作用。

Simvastatin drives a mechanism for promoting chondrogenesis of IVD cells partially mediated by upregulated BMP-2 through the inhibition of mevalonate pathway. 辛伐他汀部分通過抑制甲羥戊酸通路來上調(diào)BMP-2 ，促進(jìn)椎間盤細(xì)胞的軟骨細(xì)胞生成。

Forty-five clones were expanded through four passages and then induced for adipogenesis, osteogenesis, chondrogenesis, and neurogenesis using lineage-specific differentiation media. 通過4代擴(kuò)增得到45個(gè)克隆，并用特殊的譜系分化誘導(dǎo)液向成脂、成骨、成軟骨、神經(jīng)方向誘導(dǎo)。

Keywords myeloid progenitor cells;chondrogenesis; 骨髓祖代細(xì)胞;軟骨細(xì)胞;